BERGONIE METHOD Meaning and
Definition
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The Bergonie method refers to a technique used in radiology and radiobiology to assess the effects of radiation on living tissues. Coined after the French radiobiologists, Louis Bergonie and Louis Tribondeau, in the early 20th century, this method is designed to determine the sensitivity of different types of tissues to ionizing radiation.
By examining the responses of various tissues to radiation, the Bergonie method establishes a correlation between the radiosensitivity of a tissue and its physiological and anatomical characteristics. It takes into account two main factors: the proliferation rate and degree of differentiation of cells within a tissue.
According to the Bergonie method, highly radiosensitive tissues possess actively dividing cells that are relatively unspecialized or undifferentiated. Examples of such tissues include the hematopoietic system, gastrointestinal mucosa, and germ cells. In contrast, poorly radiosensitive tissues contain non-dividing cells that are highly specialized and differentiated, like the nervous system or cartilage.
The method also identifies the impact of physiological states on tissues' radiosensitivity. For example, tissues with high metabolism are usually more vulnerable to radiation damage, whereas a tissue's age (such as embryonic versus adult) can also influence its sensitivity.
The Bergonie method has been instrumental in guiding radiation-based medical treatments, assessing the risks associated with exposure to ionizing radiation, and understanding the dynamics of cell response to radiation-induced damage. It has significantly advanced the field of radiobiology by establishing the fundamental principles of radiation sensitivity in living organisms.
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General faradization for the reduction of fat.
A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.
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Etymology of BERGONIE METHOD
The term "Bergonie method" is named after two French radiobiologists, Louis Bergonie and Andre Gregoire. They conducted research in the early 20th century on the effects of radiation on living tissues, specifically in the field of radiation oncology. Their work focused on understanding how different types of tissues respond differently to radiation treatment, and they developed various principles and techniques based on their findings. The "Bergonie method" refers to the approach of applying radiation therapy based on the characteristics of the tumor and its surrounding tissues, taking into account factors such as cell proliferation, oxygenation, and radiosensitivity.
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