BORNA DISEASE Meaning and
Definition
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Borna disease is a neurological disorder that affects a wide range of animals and is caused by the Borna disease virus (BDV), which belongs to a group of infectious agents known as the Bornaviridae family. The virus primarily targets the central nervous system, resulting in inflammation and functional disturbances in the brain. Although originally identified in horses, Borna disease has been found in various animals, including birds, rodents, cattle, and primates.
Clinical manifestations of Borna disease can vary depending on the species and strain of the virus. In horses, the disease primarily presents as a progressive encephalopathy, characterized by behavioral changes, movement disorders, coordination deficits, and occasionally, seizures. Infection in birds has been associated with severe neurological symptoms and high mortality rates.
Diagnosis of Borna disease often involves the detection of specific antibodies or viral genetic material in the blood and cerebrospinal fluid. Post-mortem examination of the brain may also reveal characteristic changes, such as infiltration of lymphocytes and gliosis.
There is currently no approved treatment for Borna disease in animals, and management primarily involves supportive care and prevention of further spread. Although transmission to humans is considered rare, several cases of human-bornavirus infection, also known as Borna disease virus 1 (BDV-1), have been reported, mainly through occupational exposure or contact with infected animals.
In conclusion, Borna disease is a neurological disorder caused by the Borna disease virus, primarily affecting animals. It is characterized by inflammation and functional disturbances in the brain, leading to a range of clinical symptoms.
Common Misspellings for BORNA DISEASE
- vorna disease
- norna disease
- horna disease
- gorna disease
- birna disease
- bkrna disease
- blrna disease
- bprna disease
- b0rna disease
- b9rna disease
- boena disease
- bodna disease
- bofna disease
- botna disease
- bo5na disease
- bo4na disease
- borba disease
- borma disease
- borja disease
- borha disease
Etymology of BORNA DISEASE
The word "Borna" in "Borna Disease" is derived from the name of the German town in which the disease was first identified. Borna Disease is named after the town of Borna, located in the state of Saxony, Germany. The disease was first observed in horses in Borna in the late 19th century, and later, similar symptoms were identified in other animals, including humans.
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