CELLULAR RETINOIC Meaning and
Definition
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Cellular retinoic refers to a type of signaling mechanism or pathway that involves the interaction of retinoic acid with specific receptors on the surface of cells. Retinoic acid is a derivative of vitamin A and plays a crucial role in various physiological processes, including embryonic development, cell differentiation, and maintaining the health of different tissues in the body.
In the cellular retinoic pathway, retinoic acid acts as a ligand that binds to retinoic acid receptors (RARs) present in the cytoplasm of target cells. This binding event activates the receptor, causing it to translocate into the nucleus and bind to specific DNA sequences known as retinoic acid response elements (RAREs). Once bound to the DNA, the RARs can recruit co-activator proteins and initiate the transcription of specific genes.
The transcriptional activation mediated by cellular retinoic acid signaling controls the expression of numerous genes involved in various cellular processes. It not only regulates embryonic development and cell differentiation but also contributes to the maintenance and repair of epithelial tissues, immune function, and vision.
Dysregulation of the cellular retinoic acid pathway can have detrimental effects on human health. For example, deficiency or excess of retinoic acid signaling has been associated with developmental abnormalities, certain types of cancer, congenital disorders, and skin diseases. Therefore, understanding and manipulating cellular retinoic acid signaling holds great promise for clinical applications, such as in cancer therapy and regenerative medicine.
Common Misspellings for CELLULAR RETINOIC
- xellular retinoic
- vellular retinoic
- fellular retinoic
- dellular retinoic
- cwllular retinoic
- csllular retinoic
- cdllular retinoic
- crllular retinoic
- c4llular retinoic
- c3llular retinoic
- ceklular retinoic
- ceplular retinoic
- ceolular retinoic
- celkular retinoic
- celpular retinoic
- celoular retinoic
- cellylar retinoic
- cellhlar retinoic
- celljlar retinoic
- cellilar retinoic
Etymology of CELLULAR RETINOIC
The word "cellular" is derived from the Latin word "cellula", which means "small room" or "cell". In this context, it refers to the basic unit of life found in living organisms.
The word "retinoic" is derived from "retinol", which is a form of vitamin A found in animal-derived foods. Retinoic acid is a derivative of retinol and is involved in various biological processes, including cell growth and differentiation.
When combined, "cellular retinoic" refers to the cellular impact or influence of retinoic acid. It suggests that retinoic acid affects and modulates cell behavior, particularly in terms of growth and differentiation.
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