CHOLESTERYL OLEATE HYDROLASE Meaning and
Definition
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Cholesteryl oleate hydrolase (COH) is an enzyme that plays a crucial role in the metabolism of cholesterol esters in living organisms. It belongs to the ester hydrolase family of enzymes and specifically catalyzes the hydrolysis of cholesteryl oleate, which is a common cholesterol ester found in the human body.
The main function of COH is to break down cholesteryl oleate into its constituent parts, cholesterol, and oleic acid. This hydrolysis process is essential for the release of cholesterol from its storage form, allowing it to be utilized in various cellular processes such as hormone synthesis and membrane structure formation.
COH is primarily found in the lysosomes of cells, which are responsible for the digestion and recycling of cellular components. Within the lysosomes, COH acts alongside other enzymes to break down cholesterol esters into free cholesterol and fatty acids, which can then be transported and utilized by different cellular compartments.
The activity of cholesteryl oleate hydrolase is important for maintaining cholesterol homeostasis and preventing the accumulation of cholesterol esters, which can lead to the development of various diseases such as atherosclerosis and storage disorders. Deficiencies in COH expression or activity have been associated with lipid metabolism disorders and organ-specific pathologies.
In summary, cholesteryl oleate hydrolase is an enzyme that catalyzes the breakdown of cholesteryl oleate into cholesterol and oleic acid, contributing to the metabolism and utilization of cholesterol in living organisms.
Common Misspellings for CHOLESTERYL OLEATE HYDROLASE
- xholesteryl oleate hydrolase
- vholesteryl oleate hydrolase
- fholesteryl oleate hydrolase
- dholesteryl oleate hydrolase
- cgolesteryl oleate hydrolase
- cbolesteryl oleate hydrolase
- cnolesteryl oleate hydrolase
- cjolesteryl oleate hydrolase
- cuolesteryl oleate hydrolase
- cyolesteryl oleate hydrolase
- chilesteryl oleate hydrolase
- chklesteryl oleate hydrolase
- chllesteryl oleate hydrolase
- chplesteryl oleate hydrolase
- ch0lesteryl oleate hydrolase
- ch9lesteryl oleate hydrolase
- chokesteryl oleate hydrolase
- chopesteryl oleate hydrolase
- chooesteryl oleate hydrolase
- cholwsteryl oleate hydrolase
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