CHONDROITINASE ABC Meaning and
Definition
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Chondroitinase ABC is a specific enzyme that is commonly found in hospitals, research laboratories, and pharmaceutical companies. It is a protein that plays a crucial role in the breakdown and modification of chondroitin sulfate, a type of complex sugar molecule found in the extracellular matrix of connective tissues, particularly in cartilage. The enzyme's name, Chondroitinase ABC, is derived from its ability to cleave the chondroitin sulfate chains at specific points, yielding smaller fragments.
Chondroitinase ABC acts by catalyzing the hydrolysis of the glycosidic linkages present in chondroitin sulfate, leading to the fragmentation of the long chains into shorter ones. This enzymatic activity has immense therapeutic implications, especially in the field of tissue engineering and regenerative medicine, where it is often used to promote tissue repair and remodeling.
Furthermore, Chondroitinase ABC has been extensively studied for its potential in treating traumatic spinal cord injuries. By removing inhibitory chondroitin sulfate proteoglycans that form a physical barrier at the site of injury, the enzyme allows for enhanced axonal regeneration and neural plasticity, ultimately improving functional recovery.
Given its wide-ranging applications and potential therapeutic benefits, Chondroitinase ABC has become an integral tool in various scientific and medical disciplines. Researchers continue to explore its mechanisms of action and devise innovative approaches to maximize its efficacy in treating injuries and diseases associated with chondroitin sulfate accumulation.
Common Misspellings for CHONDROITINASE ABC
- xhondroitinase abc
- vhondroitinase abc
- fhondroitinase abc
- dhondroitinase abc
- cgondroitinase abc
- cbondroitinase abc
- cnondroitinase abc
- cjondroitinase abc
- cuondroitinase abc
- cyondroitinase abc
- chindroitinase abc
- chkndroitinase abc
- chlndroitinase abc
- chpndroitinase abc
- ch0ndroitinase abc
- ch9ndroitinase abc
- chobdroitinase abc
- chomdroitinase abc
- chojdroitinase abc
- chohdroitinase abc
Etymology of CHONDROITINASE ABC
The word "Chondroitinase ABC" is derived from the following components:
1. Chondroitin: The term "chondroitin" refers to a type of glycosaminoglycan, a molecule composed of repeating sugar units. It is typically found in connective tissues, such as cartilage and tendons.
2. -ase: The suffix "-ase" is commonly used in chemistry and biology to indicate an enzyme. Enzymes are proteins that catalyze specific chemical reactions.
3. ABC: The "ABC" in "Chondroitinase ABC" indicates that this particular chondroitinase is derived from a bacterium known as Proteus vulgaris. It was the third chondroitinase discovered from this organism and thus named ABC.
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