How Do You Spell PUROMYCIN AMINONUCLEOSIDE?

1. Puromycin Aminonucleoside is a synthetic antibiotic that has garnered significant interest in the field of molecular biology and medicine due to its unique properties. It is commonly used as a research tool to manipulate and study protein synthesis in cells.

   Puromycin Aminonucleoside belongs to the class of aminonucleoside antibiotics and is derived from the naturally occurring antibiotic puromycin. It functions by inhibiting protein synthesis in cells, specifically at the level of ribosomes. This antibiotic is structurally similar to the aminoacyl-tRNA molecule, and it is incorporated into the growing polypeptide chain during translation, leading to the premature termination of protein synthesis. It achieves this by acting as an analog of the 3'-end of aminoacylated tRNA, resulting in the formation of truncated, non-functional proteins.

   In biological research, Puromycin Aminonucleoside is frequently used in experiments to select for cells that contain exogenously introduced genes or to generate stable cell lines expressing specific proteins of interest. Cells that are sensitive to puromycin are eliminated when the antibiotic is added to the culture medium, while those that have been genetically modified and express a puromycin-resistant gene can survive and be selectively maintained. This property allows researchers to create cell-based models with specific gene expression patterns and study the function of different proteins.

   In summary, Puromycin Aminonucleoside is a synthetic antibiotic that interferes with protein synthesis within cells. Its ability to induce premature termination of protein translation make it a powerful tool in molecular biology research and a potential candidate for therapeutic applications in the future.

Common Misspellings for PUROMYCIN AMINONUCLEOSIDE

The word "Puromycin Aminonucleoside" is a compound term composed of two words: "puromycin" and "aminonucleoside".

1. Puromycin: The term "puromycin" is derived from the Latin word "puro", meaning "pure", and the Greek word "myco", meaning "mushroom" or "fungus". Puromycin was first isolated from the soil bacterium Streptomyces alboniger in 1950, and it was found to possess antimicrobial properties. The name "puromycin" reflects the compound's purity and its origin from a fungus-like bacterium.

2. Aminonucleoside: The term "aminonucleoside" consists of two components: "amino" and "nucleoside".