SELF PHOSPHORYLATING PROTEIN KINASE Meaning and
Definition
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Self Phosphorylating Protein Kinase, also known as autophosphorylating kinase or autophosphorylating protein kinase, is a type of enzyme that plays a crucial role in cellular signaling and regulation. It belongs to the class of protein kinases that possess the ability to phosphorylate their own amino acid residues, specifically their own tyrosine, serine, or threonine residues.
The process of self-phosphorylation occurs when the kinase molecule catalyzes the transfer of a phosphate group from ATP (adenosine triphosphate) to one or more of its own amino acid residues. This phosphorylation event leads to a conformational change in the protein structure, thereby altering its enzymatic activity. The autophosphorylation of self-phosphorylating protein kinases can occur either as an intra-molecular process or through inter-molecular interactions with other molecules.
Self-phosphorylation serves as a crucial mechanism for signal transduction pathways, as it can regulate downstream signaling events by activating or deactivating target proteins. It facilitates the transmission of signals within cells and ensures proper cellular responses to external stimuli. This process is tightly controlled in normal cellular conditions to maintain cellular homeostasis.
Abnormalities in self-phosphorylating protein kinase activity or regulation can lead to various disease states, including cancer, neurodegenerative disorders, and autoimmune diseases. Therefore, understanding the mechanisms and functions of self-phosphorylating protein kinases is vital for the development of therapeutic interventions and targeting their associated signaling pathways.
Common Misspellings for SELF PHOSPHORYLATING PROTEIN KINASE
- aelf phosphorylating protein kinase
- zelf phosphorylating protein kinase
- xelf phosphorylating protein kinase
- delf phosphorylating protein kinase
- eelf phosphorylating protein kinase
- welf phosphorylating protein kinase
- swlf phosphorylating protein kinase
- sslf phosphorylating protein kinase
- sdlf phosphorylating protein kinase
- srlf phosphorylating protein kinase
- s4lf phosphorylating protein kinase
- s3lf phosphorylating protein kinase
- sekf phosphorylating protein kinase
- sepf phosphorylating protein kinase
- seof phosphorylating protein kinase
- seld phosphorylating protein kinase
- selc phosphorylating protein kinase
- selv phosphorylating protein kinase
- selg phosphorylating protein kinase
- selt phosphorylating protein kinase
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